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Articles

1.   Menyhárd DK, Kiss-Szemán A, Tichy-Rács E, Hornung B, Rádi K, Szeltner Z, Domokos K, Szamosi I, Náray-Szabó G, Polgár L and Harmat V (2013) [23632025]
  A self-compartmentalizing hexamer serine protease from Pyrococcus horikoshii - substrate selection achieved through multimerization.
  J Biol Chem notSet,
2.   Pomozi V, Le Saux O, Brampton CN, Apana AL, Iliás A, Martin L, Szeri F, Monostory K, Paku S, Sarkadi B, Szakács G and Varadi A (2013) [23625951]
  ABCC6 is a Basolateral Plasma Membrane Protein.
  Circ Res notSet,
3.   Szilágyi A, Nussinov R and Csermely P (2013) [23409766]
  Allo-Network Drugs: Extension of the Allosteric Drug Concept to Protein-Protein Interaction and Signaling Networks.
  Curr Top Med Chem notSet,
4.   Oates ME, Romero P, Ishida T, Ghalwash M, Mizianty MJ, Xue B, Dosztányi Z, Uversky VN, Obradovic Z, Kurgan L, Dunker AK and Gough J (2013) [23203878]
  D2P2: database of disordered protein predictions.
  Nucleic Acids Res 41, D508-D516
5.   Telbisz Á, Özvegy-Laczka C, Hegedűs T, Váradi A and Sarkadi B (2013) [23205634]
  Effects of the lipid environment, cholesterol and bile acids on the function of the purified and reconstituted human ABCG2 protein.
  Biochem J 450, 387-95
6.   Závodszky P and Hajdú I (2013) [23348674]
  Evolution of the concept of conformational dynamics of enzyme functions over half of a century: A personal view.
  Biopolymers 99, 263-9
7.   Nagy GN, Marton L, Krámos B, Oláh J, Révész A, Vékey K, Delsuc F, Hunyadi-Gulyás E, Medzihradszky KF, Lavigne M, Vial H, Cerdan R and Vértessy BG (2013) [23578277]
  Evolutionary and mechanistic insights into substrate and product accommodation of CTP:phosphocholine cytidylyltransferase from Plasmodium falciparum.
  FEBS J notSet,
8.   Schad E, Kalmar L and Tompa P (2013) [23460204]
  Exon-phase symmetry and intrinsic structural disorder promote modular evolution in the human genome.
  Nucleic Acids Res notSet,
9.   Bhowmick P, Pancsa R, Guharoy M and Tompa P (2013) [23734257]
  Functional diversity and structural disorder in the human ubiquitination pathway.
  PLoS ONE 8, e65443
10.   Gál P, Dobó J, Beinrohr L, Pál G and Závodszky P (2013) [22990693]
  Inhibition of the serine proteases of the complement system.
  Adv Exp Med Biol 734, 23-40
11.   Gál P, Dobó J, Beinrohr L, Pál G and Závodszky P (2013) [23402017]
  Inhibition of the serine proteases of the complement system.
  Adv Exp Med Biol 735, 23-40
12.   Guharoy M, Szabo B, Martos SC, Kosol S and Tompa P (2013) [23761374]
  Intrinsic structural disorder in cytoskeletal proteins.
  Cytoskeleton (hoboken) notSet,
13.   Butykai A, Orbán A, Kocsis V, Szaller D, Bordács S, Tátrai-Szekeres E, Kiss LF, Bóta A, Vértessy BG, Zelles T and Kézsmárki I (2013) [23478535]
  Malaria pigment crystals as magnetic micro-rotors: key for high-sensitivity diagnosis.
  Sci Rep-uk 3, 1431
14.   Herbert C, Schieborr U, Saxena K, Juraszek J, De Smet F, Alcouffe C, Bianciotto M, Saladino G, Sibrac D, Kudlinzki D, Sreeramulu S, Brown A, Rigon P, Herault JP, Lassalle G, Blundell TL, Rousseau F, Gils A, Schymkowitz J, Tompa P, Herbert JM, Carmeliet P, Gervasio FL, Schwalbe H and Bono F (2013) [23597563]
  Molecular Mechanism of SSR128129E, an Extracellularly Acting, Small-Molecule, Allosteric Inhibitor of FGF Receptor Signaling.
  Cancer Cell 23, 489-501
15.   Bánóczi Z, Tantos A, Farkas A, Majer Z, Dókus LE, Tompa P and Hudecz F (2013) [23613308]
  New m-calpain substrate-based azapeptide inhibitors.
  J Pept Sci notSet,
16.   Závodszky P (2013) [23738340]
  Péter Friedrich (1936-2013).
  FEBS Lett 587, 1269-70
17.   Kozma D, Simon I and Tusnády GE (2013) [23203988]
  PDBTM: Protein Data Bank of transmembrane proteins after 8 years.
  Nucleic Acids Res 41, D524-9
18.   Uitto J, Váradi A, Bercovitch L, Terry PF and Terry SF (2013) [23673496]
  Pseudoxanthoma Elasticum: Progress in Research Toward Treatment: Summary of the 2012 PXE International Research Meeting.
  J Invest Dermatol 133, 1444-1449
19.   Megyeri M, Harmat V, Major B, Végh Á, Balczer J, Héja D, Szilágyi K, Datz D, Pál G, Závodszky P, Gál P and Dobó J (2013) [23386610]
  Quantitative characterization of the activation steps of mannan-binding lectin (MBL)-associated serine proteases (MASPs) points to the central role of MASP-1 in the initiation of the complement lectin pathway.
  J Biol Chem 288, 8922-34
20.   Varga A, Gráczer E, Chaloin L, Liliom K, Závodszky P, Lionne C and Vas M (2013) [23201309]
  Selectivity of kinases on the activation of tenofovir, an anti-HIV agent.
  Eur J Pharm Sci 48, 307-15
21.   Norris V, Amar P, Legent G, Ripoll C, Thellier M and Ovádi J (2013) [23398642]
  Sensor potency of the moonlighting enzyme-decorated cytoskeleton: the cytoskeleton as a metabolic sensor.
  BMC Biochem 14, 3
22.   Sugár IP, Simon I and Chong PL (2013) [23746517]
  Series of concentration-induced phase transitions in cholesterol/phosphatidylcholine mixtures.
  Biophys J 104, 2448-55
23.   Tantos A, Szrnka K, Szabo B, Bokor M, Kamasa P, Matus P, Bekesi A, Tompa K, Han KH and Tompa P (2013) [22906532]
  Structural disorder and local order of hNopp140.
  Bba-proteins Proteom 1834, 342-50
24.   Paréj K, Dobó J, Závodszky P and Gál P (2013) [23399388]
  The control of the complement lectin pathway activation revisited: Both C1-inhibitor and antithrombin are likely physiological inhibitors, while α(2)-macroglobulin is not.
  Mol Immunol 54, 415-422
25.   Szeltner Z, Juhász T, Szamosi I, Rea D, Fülöp V, Módos K, Juliano L and Polgár L (2013) [22940581]
  The loops facing the active site of prolyl oligopeptidase are crucial components in substrate gating and specificity.
  Biochim Biophys Acta 1834, 98-111
26.   Csuka D, Munthe-Fog L, Skjoedt MO, Kocsis A, Zotter Z, Gál P, Varga L, Farkas H, Füst G and Garred P (2013) [23318225]
  The role of ficolins and MASPs in hereditary angioedema due to C1-inhibitor deficiency.
  Mol Immunol 54, 271-277
27.   Arányi T, Bacquet C, de Boussac H, Ratajewski M, Pomozi V, Fülöp K, Brampton CN, Pulaski L, Saux OL and Váradi A (2013) [23483032]
  Transcriptional regulation of the ABCC6 gene and the background of impaired function of missense disease-causing mutations.
  Front Genet 4, 27
28.   Gráczer É, Lionne C, Závodszky P, Chaloin L and Vas M (2013) [23421786]
  Transient kinetic studies reveal isomerization steps along the kinetic pathway of Thermus thermophilus 3-isopropylmalate dehydrogenase.
  FEBS J 280, 1764-72
29.   Abrusán G, Szilágyi A, Zhang Y and Papp B (2013) [23341038]
  Turning gold into \'junk\': transposable elements utilize central proteins of cellular networks.
  Nucleic Acids Res 41, 3190-3200
30.   Flachner B, Lörincz Z, Carotti A, Nicolotti O, Kuchipudi P, Remez N, Sanz F, Tóvári J, Szabó MJ, Bertók B, Cseh S, Mestres J and Dormán G (2012) [22558171]
  A chemocentric approach to the identification of cancer targets.
  PLoS ONE 7, e35582
31.   Orosz F (2012) [23053195]
  A fish-specific member of the TPPP protein family?
  J Mol Evol 75, 55-72
32.   Orosz F (2012) [23166627]
  A New Protein Superfamily: TPPP-Like Proteins.
  PLoS ONE 7, e49276
33.   Cho HJ, Park HJ, Trexler M, Venselaar H, Lee KY, Robertson NG, Baek JI, Kang BS, Morton CC, Vriend G, Patthy L and Kim UK (2012) [22610276]
  A novel COCH mutation associated with autosomal dominant nonsyndromic hearing loss disrupts the structural stability of the vWFA2 domain.
  J Mol Med 90, 1321-31
34.   Tátrai P, Sági B, Szigeti A, Szepesi A, Szabó I, Bősze S, Kristóf Z, Markó K, Szakács G, Urbán I, Mező G, Uher F and Német K (2012) [23135412]
  A novel cyclic RGD-containing peptide polymer improves serum-free adhesion of adipose tissue-derived mesenchymal stem cells to bone implant surfaces.
  J Mater Sci-mater M notSet,
35.   Ratajewski M, de Boussac H, Sachrajda I, Bacquet C, Kovács T, Váradi A, Pulaski L and Arányi T (2012) [22763786]
  ABCC6 expression is regulated by CCAAT/enhancer-binding protein activating a primate-specific sequence located in the first intron of the gene.
  J Invest Dermatol 132, 2709-17
36.   Varga A, Marcus AP, Himoto M, Iwai S and Szüts D (2012) [23272247]
  Analysis of CPD Ultraviolet Lesion Bypass in Chicken DT40 Cells: Polymerase η and PCNA Ubiquitylation Play Identical Roles.
  PLoS ONE 7, e52472
37.   Telbisz A, Hegedüs C, Ozvegy-Laczka C, Goda K, Várady G, Takáts Z, Szabó E, Sorrentino BP, Váradi A and Sarkadi B (2012) [22115866]
  Antibody binding shift assay for rapid screening of drug interactions with the human ABCG2 multidrug transporter.
  Eur J Pharm Sci 45, 101-9
38.   Bányai L, Kerekes K and Patthy L (2012) [22986341]
  Characterization of a Wnt-binding site of the WIF-domain of Wnt inhibitory factor-1.
  FEBS Lett 586, 3122-6
39.   Meggyesi N, Kalmár L, Fekete S, Masszi T, Tordai A and Andrikovics H (2012) [22038725]
  Characterization of ABL exon 7 deletion by molecular genetic and bioinformatic methods reveals no association with imatinib resistance in chronic myeloid leukemia.
  Med Oncol 29, 2136-42
40.   Kozma D, Simon I and Tusnády GE (2012) [22669913]
  CMWeb: an interactive on-line tool for analysing residue-residue contacts and contact prediction methods.
  Nucleic Acids Res 40, W329-33
41.   Pesti S, Balázs A, Udupa R, Szabó B, Fekete A, B Gel G and Buday L (2012) [23181695]
  Complex formation of EphB1/Nck/Caskin1 leads to tyrosine phosphorylation and structural changes of the Caskin1 SH3 domain.
  Cell Commun Signal 10, 36
42.   Mészáros B, Dosztányi Z and Simon I (2012) [23056474]
  Disordered Binding Regions and Linear Motifs-Bridging the Gap between Two Models of Molecular Recognition.
  PLoS ONE 7, e46829
43.   Kovacs D and Tompa P (2012) [22988848]
  Diverse functional manifestations of intrinsic structural disorder in molecular chaperones.
  Biochem Soc T 40, 963-8
44.   Hess K, Ajjan R, Phoenix F, Dobó J, Gál P and Schroeder V (2012) [22536427]
  Effects of MASP-1 of the Complement System on Activation of Coagulation Factors and Plasma Clot Formation.
  PLoS ONE 7, e35690
45.   Horváti K, Bacsa B, Szabó N, Dávid S, Mező G, Grolmusz V, Vértessy BG, Hudecz F and Bősze S (2012) [22515329]
  Enhanced Cellular Uptake of a New, in Silico Identified Antitubercular Candidate by Peptide Conjugation.
  Bioconjugate Chem 23, 900-7
46.   Horváth A, Békési A, Muha V, Erdélyi M and Vértessy BG (2012) [23238493]
  Expanding the DNA alphabet in the fruit fly: Uracil enrichment in genomic DNA.
  Fly 7,
47.   Kasza I, Várady G, Andrikovics H, Koszarska M, Tordai A, Scheffer GL, Németh A, Szakács G and Sarkadi B (2012) [23166586]
  Expression Levels of the ABCG2 Multidrug Transporter in Human Erythrocytes Correspond to Pharmacologically Relevant Genetic Variations.
  PLoS ONE 7, e48423
48.   Bögel G, Gujdár A, Geiszt M, Lányi Á, Fekete A, Sipeki S, Downward J and Buday L (2012) [22829589]
  Frank-ter Haar syndrome protein Tks4 regulates epidermal growth factor-dependent cell migration.
  J Biol Chem 287, 31321-9
49.   Fuxreiter M (2012) [21927770]
  Fuzziness: linking regulation to protein dynamics.
  Mol Biosyst 8, 168-77
50.   Fuxreiter M and Tompa P (2012) [22399315]
  Fuzzy complexes: a more stochastic view of protein function.
  Adv Exp Med Biol 725, 1-14
51.   Tantos A and Tompa P (2012) [22821526]
  Identification of Intrinsically Disordered Proteins by a Special 2D Electrophoresis.
  Methods Mol Biol 896, 215-22
52.   Varga A, Palmai Z, Gugolya Z, Gráczer E, Vonderviszt F, Závodszky P, Balog E and Vas M (2012) [23231058]
  Importance of aspartate residues in balancing the flexibility and fine-tuning the catalysis of human 3-phosphoglycerate kinase.
  Biochemistry-us 51, 10197-207
53.   Hegyi H and Tompa P (2012) [22105808]
  Increased structural disorder of proteins encoded on human sex chromosomes.
  Mol Biosyst 8, 229-36
54.   Hegedüs C, Truta-Feles K, Antalffy G, Várady G, Német K, Ozvegy-Laczka C, Kéri G, Orfi L, Szakács G, Settleman J, Váradi A and Sarkadi B (2012) [22548830]
  Interaction of the EGFR inhibitors gefitinib, vandetanib, pelitinib and neratinib with the ABCG2 multidrug transporter: implications for the emergence and reversal of cancer drug resistance.
  Biochem Pharmacol 84, 260-7
55.   Szilágyi A, Zhang Y and Závodszky P (2012) [22079367]
  Intra-chain 3D segment swapping spawns the evolution of new multidomain protein architectures.
  J Mol Biol 415, 221-35
56.   Tantos A, Han KH and Tompa P (2012) [21782886]
  Intrinsic disorder in cell signaling and gene transcription.
  Mol Cell Endocrinol 348, 457-65
57.   Kovacs D, Szabo B, Pancsa R and Tompa P (2012) [23142500]
  Intrinsically disordered proteins undergo and assist folding transitions in the proteome.
  Arch Biochem Biophys notSet,
58.   Tompa P (2012) [22989858]
  Intrinsically disordered proteins: a 10-year recap.
  Trends Biochem Sci 37, 509-16
59.   Pajkos M, Mészáros B, Simon I and Dosztányi Z (2012) [21918772]
  Is there a biological cost of protein disorder? Analysis of cancer-associated mutations.
  Mol Biosyst 8, 296-307
60.   Kalmar L, Acs V, Silhavy D and Tompa P (2012) [22971338]
  Long-range interactions in nonsense-mediated mRNA decay are mediated by intrinsically disordered protein regions.
  J Mol Biol 424, 125-31
61.   Thiel S, Jensen L, Degn SE, Nielsen HJ, Gál P, Dobó J and Jensenius JC (2012) [22670777]
  Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules: normal and acute-phase levels in serum and stoichiometry of lectin pathway components.
  Clin Exp Immunol 169, 38-48
62.   Horvath I, Weise CF, Andersson EK, Chorell E, Sellstedt M, Bengtsson C, Olofsson A, Hultgren SJ, Chapman M, Wolf-Watz M, Almqvist F and Wittung-Stafshede P (2012) [22260746]
  Mechanisms of protein oligomerization: inhibitor of functional amyloids templates α-synuclein fibrillation.
  J Am Chem Soc 134, 3439-44
63.   Oláh J, Zotter Á, Hlavanda E, Szunyogh S, Orosz F, Szigeti K, Fidy J and Ovádi J (2012) [22484033]
  Microtubule assembly-derived by dimerization of TPPP/p25. Evaluation of thermodynamic parameters for multiple equilibrium system from ITC data.
  Bba-gen Subjects 1820, 785-94
64.   Kaszuba K, Róg T, Danne R, Canning P, Fülöp V, Juhász T, Szeltner Z, St Pierre JF, García-Horsman A, Männistö PT, Karttunen M, Hokkanen J and Bunker A (2012) [22484394]
  Molecular dynamics, crystallography and mutagenesis studies on the substrate gating mechanism of prolyl oligopeptidase.
  Biochimie 94, 1398-411
65.   Magazu S, Migliardo F, Gonzalez MA, Mondelli C, Parker SF and Vertessy BG (2012) [-100052455]
  Molecular Mechanisms of Survival Strategies in Extreme Conditions.
  Life 2, 364-76
66.   Héja D, Harmat V, Fodor K, Wilmanns M, Dobó J, Kékesi KA, Závodszky P, Gál P and Pál G (2012) [22511776]
  Monospecific inhibitors show that both mannan-binding lectin-associated serine protease-1 (MASP-1) and -2 Are essential for lectin pathway activation and reveal structural plasticity of MASP-2.
  J Biol Chem 287, 20290-300
67.   Tompa P (2012) [22710296]
  On the supertertiary structure of proteins.
  Nat Chem Biol 8, 597-600
68.   Hegedüs C, Truta-Feles K, Antalffy G, Brózik A, Kasza I, Német K, Orbán TI, Özvegy-Laczka C, Váradi A and Sarkadi B (2012) [22449574]
  PI3-kinase and mTOR inhibitors differently modulate the function of the ABCG2 multidrug transporter.
  Biochem Bioph Res Co 420, 869-74
69.   Poppe L, Paizs C, Kovács K, Irimie FD and Vértessy B (2012) [21956553]
  Preparation of unnatural amino acids with ammonia-lyases and 2,3-aminomutases.
  Methods Mol Biol 794, 3-19
70.   Adám C, Erdei E, Casado C, Kovács L, González A, Majoros L, Petrényi K, Bagossi P, Farkas I, Molnar M, Pócsi I, Ariño J and Dombrádi V (2012) [22343349]
  Protein phosphatase CaPpz1 is involved in cation homeostasis, cell wall integrity and virulence of Candida albicans.
  Microbiol-sgm 158, 1258-67
71.   Leiter E, González A, Erdei E, Casado C, Kovács L, Adám C, Oláh J, Miskei M, Molnar M, Farkas I, Hamari Z, Ariño J, Pócsi I and Dombrádi V (2012) [22750657]
  Protein phosphatase Z modulates oxidative stress response in fungi.
  Fungal Genet Biol 49, 708-16
72.   Tantos A and Tompa P (2012) [22821542]
  Proteomic methods for the identification of intrinsically disordered proteins.
  Methods Mol Biol 896, 429-37
73.   Györffy D, Závodszky P and Szilágyi A (2012) [23221093]
  Pull moves for rectangular lattice polymer models are not fully reversible.
  Ieee Acm T Comput Bi 9, 1847-9
74.   Bernstein N, Várnai C, Solt I, Winfield SA, Payne MC, Simon I, Fuxreiter M and Csányi G (2012) [22089416]
  QM/MM simulation of liquid water with an adaptive quantum region.
  Phys Chem Chem Phys 14, 646-656
75.   Yamagata Y, Szabó P, Szüts D, Bacquet C, Arányi T and Páldi A (2012) [22395463]
  Rapid turnover of DNA methylation in human cells.
  Epigenetics 7, 141-5
76.   Héja D, Kocsis A, Dobó J, Szilágyi K, Szász R, Závodszky P, Pál G and Gál P (2012) [22691502]
  Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2.
  P Natl Acad Sci Usa 109, 10498-503
77.   Kiss K, Brozik A, Kucsma N, Toth A, Gera M, Berry L, Vallentin A, Vial H, Vidal M and Szakacs G (2012) [22655043]
  Shifting the Paradigm: The Putative Mitochondrial Protein ABCB6 Resides in the Lysosomes of Cells and in the Plasma Membrane of Erythrocytes.
  PLoS ONE 7, e37378
78.   de Boussac H, Orbán TI, Várady G, Tihanyi B, Bacquet C, Brózik A, Váradi A, Sarkadi B and Arányi T (2012) [22922104]
  Stimulus-induced expression of the ABCG2 multidrug transporter in HepG2 hepatocarcinoma model cells involves the ERK1/2 cascade and alternative promoters.
  Biochem Bioph Res Co 426, 172-6
79.   Kidmose RT, Laursen NS, Dobó J, Kjaer TR, Sirotkina S, Yatime L, Sottrup-Jensen L, Thiel S, Gál P and Andersen GR (2012) [22949645]
  Structural basis for activation of the complement system by component C4 cleavage.
  P Natl Acad Sci Usa 109, 15425-30
80.   Pancsa R and Tompa P (2012) [22496841]
  Structural disorder in eukaryotes.
  PLoS ONE 7, e34687
81.   Kalmar L, Homola D, Varga G and Tompa P (2012) [22634174]
  Structural disorder in proteins brings order to crystal growth in biomineralization.
  Bone 51, 528-34
82.   Pecsi I, Hirmondo R, Brown AC, Lopata A, Parish T, Vertessy BG and Tóth J (2012) [22655049]
  The dUTPase Enzyme Is Essential in Mycobacterium smegmatis.
  PLoS ONE 7, e37461
83.   Le Saux O, Martin L, Aherrahrou Z, Leftheriotis G, Váradi A and Brampton CN (2012) [23248644]
  The molecular and physiological roles of ABCC6: more than meets the eye.
  Front Genet 3, 289
84.   Vonderviszt F, Sajó R, Dobó J and Závodszky P (2012) [22160896]
  The Use of a Flagellar Export Signal for the Secretion of Recombinant Proteins in Salmonella.
  Methods Mol Biol 824, 131-143
85.   Muha V, Horváth A, Békési A, Pukáncsik M, Hodoscsek B, Merényi G, Róna G, Batki J, Kiss I, Jankovics F, Vilmos P, Erdélyi M and Vértessy BG (2012) [22685418]
  Uracil-containing DNA in Drosophila: stability, stage-specific accumulation, and developmental involvement.
  PLoS Genet 8, e1002738
86.   Tompa K, Bokor M and Tompa P (2012) [22760320]
  Wide-line NMR and protein hydration.
  Methods Mol Biol 895, 167-96