Center of Excellence of the European Union
Home
Research
Services
Education
About us
Eva Graczer
Dictionary
Publications
Publications
Articles
1.
Varga A
,
Gráczer E
, Chaloin L,
Liliom K
,
Závodszky P
, Lionne C and
Vas M
(2013) [23201309]
Selectivity of kinases on the activation of tenofovir, an anti-HIV agent.
Eur J Pharm Sci
48
, 307-15
2.
Varga A
, Palmai Z, Gugolya Z,
Gráczer E
, Vonderviszt F,
Závodszky P
, Balog E and
Vas M
(2012) [23231058]
Importance of aspartate residues in balancing the flexibility and fine-tuning the catalysis of human 3-phosphoglycerate kinase.
Biochemistry-us
51
, 10197-207
3.
Zerrad L, Merli A, Schröder GF,
Varga A
,
Gráczer É
, Pernot P, Round A,
Vas M
and Bowler MW (2011) [21349853]
A spring-loaded release mechanism regulates domain movement and catalysis in phosphoglycerate kinase.
J Biol Chem
286
, 14040-8
4.
Gráczer E
, Konarev PV,
Szimler T
,
Bacsó A
,
Bodonyi A
, Svergun DI,
Závodszky P
and
Vas M
(2011) [21939659]
Essential role of the metal-ion in the IPM-assisted domain closure of 3-isopropylmalate dehydrogenase.
FEBS Lett
585
, 3297-302
5.
Varga A
, Chaloin L, Sági G, Sendula R,
Gráczer E
,
Liliom K
,
Závodszky P
, Lionne C and
Vas M
(2011) [21505655]
Nucleotide promiscuity of 3-phosphoglycerate kinase is in focus: implications for the design of better anti-HIV analogues.
Mol Biosyst
7
, 1863-73
6.
Merli A, Manikandan K,
Gráczer E
, Schuldt L, Singh RK,
Závodszky P
,
Vas M
and Weiss MS (2010) [20516614]
Crystallization and preliminary X-ray diffraction analysis of various enzyme-substrate complexes of isopropylmalate dehydrogenase from Thermus thermophilus.
Acta Crystallogr F
66
, 738-43
7.
Vas M
,
Varga A
and
Gráczer E
(2010) [20088776]
Insight into the mechanism of domain movements and their role in enzyme function: example of 3-phosphoglycerate kinase.
Curr Protein Pept Sc
11
, 118-47
8.
Gráczer É
,
Varga A
,
Hajdú I
, Melnik B,
Szilágyi A
, Semisotnov G,
Závodszky P
and
Vas M
(2007) [17887729]
Rates of unfolding, rather than refolding, determine thermal stabilities of thermophilic, mesophilic, and psychrotrophic 3-isopropylmalate dehydrogenases.
Biochemistry-us
46
, 11536-49
9.
Varga A
,
Flachner B
, Konarev P,
Gráczer É
,
Szabó J
, Svergun D,
Závodszky P
and
Vas M
(2006) [16647059]
Substrate-induced double sided H-bond network as a means of domain closure in 3-phosphoglycerate kinase.
FEBS Lett
580
, 2698-706
10.
Varga A
,
Flachner B
,
Gráczer É
, Osváth S,
Szilágyi AN
and
Vas M
(2005) [15819882]
Correlation between conformational stability of the ternary enzyme-substrate complex and domain closure of 3-phosphoglycerate kinase.
FEBS J
272
, 1867-85