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Recent publications

Articles

1.   Kovári J, Barabás O, Varga B, Békési A, Tölgyesi F, Fidy J, Nagy J and Vértessy BG (2008) [17932923]
  Methylene substitution at the alpha-beta bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site.
  Proteins 71, 308-19
2.   Varga B, Barabás O, Kovári J, Tóth J, Hunyadi-Gulyás E, Klement E, Medzihradszky KF, Tölgyesi F, Fidy J and Vértessy BG (2007) [17880943]
  Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase.
  FEBS Lett 581, 4783-8
3.   Kovári J, Barabás O, Takács E, Békési A, Dubrovay Z, Pongrácz V, Zagyva I, Imre T, Szabó P and Vértessy BG (2004) [14724274]
  Altered active site flexibility and a structural metal-binding site in eukaryotic dUTPase: kinetic characterization, folding, and crystallographic studies of the homotrimeric Drosophila enzyme.
  J Biol Chem 279, 17932-44
4.   Békési A, Zagyva I, Hunyadi-Gulyás E, Pongrácz V, Kovári J, Nagy AO, Erdei A, Medzihradszky KF and Vértessy BG (2004) [14996835]
  Developmental regulation of dUTPase in Drosophila melanogaster.
  J Biol Chem 279, 22362-70
5.   Kovári J, Imre T, Szabó P and Vértessy BG (2004) [15571280]
  Mechanistic studies of dUTPases.
  Nucleos Nucleot Nucl 23, 1475-9
6.   Barabás O, Pongrácz V, Kovári J, Wilmanns M and Vértessy BG (2004) [15208312]
  Structural insights into the catalytic mechanism of phosphate ester hydrolysis by dUTPase.
  J Biol Chem 279, 42907-15