Center of Excellence of the European Union
 
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Recent publications

Articles

1.   Tömöri T, Hajdú I, Barna L, Lőrincz Z, Cseh S and Dormán G (2011) [21947759]
  Combining 2D and 3D in silico methods for rapid selection of potential PDE5 inhibitors from multimillion compounds repositories: biological evaluation.
  Mol Divers 16, 59-72
2.   Major B, Kardos J, Kékesi KA, Lorincz Z, Závodszky P and Gál P (2010) [20178990]
  Calcium-dependent conformational flexibility of a CUB domain controls activation of the complement serine protease C1r.
  J Biol Chem 285, 11863-9
3.   Beinrohr L, Harmat V, Dobó J, Lörincz Z, Gál P and Závodszky P (2007) [17488724]
  C1 inhibitor serpin domain structure reveals the likely mechanism of heparin potentiation and conformational disease.
  J Biol Chem 282, 21100-9
4.   Molnár L, Keseru GM, Papp A, Lorincz Z, Ambrus G and Darvas F (2006) [16288868]
  A neural network based classification scheme for cytotoxicity predictions:Validation on 30,000 compounds.
  Bioorg Med Chem Lett 16, 1037-9
5.   Dormán G, Puskás LG, Fehér LZ, Hackler L, Lorincz Z, Lang C, Urge L and Darvas F (2006) [17094670]
  [Comparative chemical proteomics: simultaneous identification of disease-specific protein targets and their small molecule-binding partners, suitable as drug candidates]
  Acta Pharm Hung 76, 3-9
6.   Varga L, Szilágyi K, Lőrincz Z, Berrens L, Thiel S, Závodszky P, Daha MR, Thielens NM, Arlaud GJ, Nagy K, Späth P and Füst G (2003) [12686499]
  Studies on the mechanisms of allergen-induced activation of the classical and lectin pathways of complement.
  Mol Immunol 39, 839-46
7.   Kalabay L, Jakab L, Prohászka Z, Füst G, Benkö Z, Telegdy L, Lőrincz Z, Závodszky P, Arnaud P and Fekete B (2002) [11943951]
  Human fetuin/alpha2HS-glycoprotein level as a novel indicator of liver cell function and short-term mortality in patients with liver cirrhosis and liver cancer.
  Eur J Gastroen Hepat 14, 389-94
8.   Wang DA, Lorincz Z, Bautista DL, Liliom K, Tigyi G and Parrill AL (2001) [11604399]
  A single amino acid determines lysophospholipid specificity of the S1P1 (EDG1) and LPA1 (EDG2) phospholipid growth factor receptors.
  J Biol Chem 276, 49213-20
9.   Kardos J, Gál P, Szilágyi L, Thielens NM, Szilágyi K, Lőrincz Z, Kulcsár P, Gráf L, Arlaud GJ and Závodszky P (2001) [11673533]
  The role of the individual domains in the structure and function of the catalytic region of a modular serine protease, C1r.
  J Immunol 167, 5202-8
10.   Parrill AL, Wang D, Bautista DL, Van Brocklyn JR, Lorincz Z, Fischer DJ, Baker DL, Liliom K, Spiegel S and Tigyi G (2000) [10982820]
  Identification of Edg1 receptor residues that recognize sphingosine 1-phosphate.
  J Biol Chem 275, 39379-84
11.   Lörincz Z, Gál P, Dobó J, Cseh S, Szilágyi K, Ambrus G and Závodszky P (2000) [10925288]
  The cleavage of two C1s subunits by a single active C1r reveals substantial flexibility of the C1s-C1r-C1r-C1s tetramer in the C1 complex.
  J Immunol 165, 2048-51
12.   Dobó J, Gál P, Szilágyi K, Cseh S, Lörincz Z, Schumaker VN and Závodszky P (1999) [9916740]
  One active C1r subunit is sufficient for the activity of the complement C1 complex: stabilization of C1r in the zymogen form by point mutations.
  J Immunol 162, 1108-12
13.   Lőrincz Z, Kalabay L, Cseh S, Závodszky P, Arnaud P and Jakab L (1998) [9873947]
  Isolation of human alpha 2HS-glycoprotein synthesized by Sf9 cells.
  Acta Microbiol Imm H 45, 419-24
14.   Cseh S, Gál P, Sárvári M, Dobó J, Lőrincz Z, Schumaker VN and Závodszky P (1996) [8676886]
  Functional effects of domain deletions in a multidomain serine protease, C1r.
  Mol Immunol 33, 351-9

Books or book chapters

1.   Gal P, Ambrus G, Lorincz Z and Zavodszky P (2004)
  The initiation complexes of the classical and lectin patways.
  The complement system. Novel roles in health and disease. , 19-43