Center of Excellence of the European Union
 
Set page width to 1024
Login
 
Recent publications

Articles

1.   Pecsi I, Hirmondo R, Brown AC, Lopata A, Parish T, Vertessy BG and Tóth J (2012) [22655049]
  The dUTPase Enzyme Is Essential in Mycobacterium smegmatis.
  PLoS ONE 7, e37461
2.   Merényi G, Kovári J, Tóth J, Takács E, Zagyva I, Erdei A and Vértessy BG (2011) [21780905]
  Cellular Response to Efficient dUTPase RNAi Silencing in Stable HeLa Cell Lines Perturbs Expression Levels of Genes Involved in Thymidylate Metabolism.
  Nucleos Nucleot Nucl 30, 369-90
3.   Pécsi I, Szabó JE, Adams SD, Simon I, Sellers JR, Vértessy BG and Tóth J (2011) [21831832]
  Nucleotide pyrophosphatase employs a P-loop-like motif to enhance catalytic power and NDP/NTP discrimination.
  P Natl Acad Sci Usa 108, 14437-14442
4.   Mészáros B, Tóth J, Vértessy BG, Dosztányi Z and Simon I (2011) [21814507]
  Proteins with Complex Architecture as Potential Targets for Drug Design: A Case Study of Mycobacterium tuberculosis.
  PLoS Comput Biol 7, e1002118
5.   Erdélyi P, Borsos E, Takács-Vellai K, Kovács T, Kovács AL, Sigmond T, Hargitai B, Pásztor L, Sengupta T, Dengg M, Pécsi I, Tóth J, Nilsen H, Vértessy BG and Vellai T (2011) [21502138]
  Shared developmental roles and transcriptional control of autophagy and apoptosis in Caenorhabditis elegans.
  J Cell Sci 124, 1510-8
6.   Pecsi I, Leveles I, Harmat V, Vertessy BG and Toth J (2010) [20601405]
  Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase.
  Nucleic Acids Res 38, 7179-86
7.   Takács E, Nagy G, Leveles I, Harmat V, Lopata A, Tóth J and Vértessy BG (2010) [20493855]
  Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases.
  FEBS Lett 584, 3047-54
8.   Kovacs E, Tóth J, Vértessy BG and Liliom K (2010) [19910470]
  Dissociation of calmodulin-target peptide complexes by the lipid mediator sphingosylphosphorylcholine: implications in calcium signaling.
  J Biol Chem 285, 1799-808
9.   Kovacs E, Harmat V, Tóth J, Vértessy BG, Módos K, Kardos J and Liliom K (2010) [20522785]
  Structure and mechanism of calmodulin binding to a signaling sphingolipid reveal new aspects of lipid-protein interactions.
  FASEB J 24, 3829-39
10.   Vértessy BG and Tóth J (2009) [18837522]
  Keeping uracil out of DNA: physiological role, structure and catalytic mechanism of dUTPases.
  Accounts Chem Res 42, 97-106
11.   Forgacs E, Sakamoto T, Cartwright S, Belknap B, Kovács M, Tóth J, Webb MR, Sellers JR and White HD (2009) [19008235]
  Switch 1 mutation S217A converts myosin V into a low duty ratio motor.
  J Biol Chem 284, 2138-49
12.   Varga B, Barabás O, Kovári J, Tóth J, Hunyadi-Gulyás E, Klement E, Medzihradszky KF, Tölgyesi F, Fidy J and Vértessy BG (2007) [17880943]
  Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase.
  FEBS Lett 581, 4783-8
13.   Tóth J, Varga B, Kovács M, Málnási-Csizmadia A and Vértessy BG (2007) [17848562]
  Kinetic mechanism of human dUTPase, an essential nucleotide pyrophosphatase enzyme.
  J Biol Chem 282, 33572-82
14.   Kempler K, Tóth J, Yamashita R, Mapel G, Robinson K, Cardasis H, Stevens S, Sellers JR and Battelle BA (2007) [17367164]
  Loop 2 of limulus myosin III is phosphorylated by protein kinase A and autophosphorylation.
  Biochemistry-us 46, 4280-93
15.   Málnási-Csizmadia A, Tóth J, Pearson DS, Hetényi C, Nyitray L, Geeves MA, Bagshaw CR and Kovács M (2007) [17449872]
  Selective perturbation of the myosin recovery stroke by point mutations at the base of the lever arm affects ATP hydrolysis and phosphate release.
  J Biol Chem 282, 17658-64
16.   Tóth J, Kovács M, Wang F, Nyitray L and Sellers JR (2005) [15980429]
  Myosin V from Drosophila reveals diversity of motor mechanisms within the myosin V family.
  J Biol Chem 280, 30594-603
17.   Lucas-Lopez C, Patterson S, Blum T, Straight AF, Toth J, Slawin AMZ, Mitchison TJ, Sellers JR and Westwood NJ (2005) [-100002947]
  Stereochemical Assignment and Fluorescence Tuning of the Small Molecule Tool, (-)-Blebbistatin.
  Eur J Org Chem 2005, 1736-1740
18.   Kovács M, Tóth J, Málnási-Csizmadia A, Bagshaw CR and Nyitray L (2004) [15160493]
  Engineering lysine reactivity as a conformational sensor in the Dictyostelium myosin II motor domain.
  J Muscle Res Cell M 25, 95-102
19.   Kovács M, Tóth J, Hetényi C, Málnási-Csizmadia A and Sellers JR (2004) [15205456]
  Mechanism of blebbistatin inhibition of myosin II.
  J Biol Chem 279, 35557-63
20.   Kovács M, Tóth J, Nyitray L and Sellers JR (2004) [15065866]
  Two-headed binding of the unphosphorylated nonmuscle heavy meromyosin.ADP complex to actin.
  Biochemistry-us 43, 4219-26
21.   Toth J, Boszormenyi I, Majer ZS, Laczko I, Malvy C, Hollosi M and Bertrand JR (2002) [12054557]
  A two step model aimed at delivering antisense oligonucleotides in targeted cells.
  Biochem Bioph Res Co 293, 18-22