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Selected publications
Articles
1.
Pomozi V
, Le Saux O, Brampton CN, Apana AL,
Iliás A
, Martin L,
Szeri F
, Monostory K, Paku S, Sarkadi B,
Szakács G
and
Varadi A
(2013) [23625951]
ABCC6 is a Basolateral Plasma Membrane Protein.
Circ Res
notSet
,
2.
Telbisz Á, Özvegy-Laczka C,
Hegedűs T
,
Váradi A
and
Sarkadi B
(2013) [23205634]
Effects of the lipid environment, cholesterol and bile acids on the function of the purified and reconstituted human ABCG2 protein.
Biochem J
450
, 387-95
3.
Uitto J,
Váradi A
, Bercovitch L, Terry PF and Terry SF (2013) [23673496]
Pseudoxanthoma Elasticum: Progress in Research Toward Treatment: Summary of the 2012 PXE International Research Meeting.
J Invest Dermatol
133
, 1444-1449
4.
Arányi T
,
Bacquet C
, de Boussac H, Ratajewski M,
Pomozi V
, Fülöp K, Brampton CN, Pulaski L, Saux OL and
Váradi A
(2013) [23483032]
Transcriptional regulation of the ABCC6 gene and the background of impaired function of missense disease-causing mutations.
Front Genet
4
, 27
5.
Ratajewski M, de Boussac H, Sachrajda I,
Bacquet C
, Kovács T,
Váradi A
, Pulaski L and
Arányi T
(2012) [22763786]
ABCC6 expression is regulated by CCAAT/enhancer-binding protein activating a primate-specific sequence located in the first intron of the gene.
J Invest Dermatol
132
, 2709-17
6.
Telbisz A, Hegedüs C, Ozvegy-Laczka C, Goda K, Várady G, Takáts Z, Szabó E, Sorrentino BP,
Váradi A
and Sarkadi B (2012) [22115866]
Antibody binding shift assay for rapid screening of drug interactions with the human ABCG2 multidrug transporter.
Eur J Pharm Sci
45
, 101-9
7.
Hegedüs C, Truta-Feles K, Antalffy G, Várady G, Német K, Ozvegy-Laczka C, Kéri G, Orfi L,
Szakács G
, Settleman J,
Váradi A
and
Sarkadi B
(2012) [22548830]
Interaction of the EGFR inhibitors gefitinib, vandetanib, pelitinib and neratinib with the ABCG2 multidrug transporter: implications for the emergence and reversal of cancer drug resistance.
Biochem Pharmacol
84
, 260-7
8.
Hegedüs C, Truta-Feles K, Antalffy G, Brózik A, Kasza I, Német K, Orbán TI, Özvegy-Laczka C,
Váradi A
and Sarkadi B (2012) [22449574]
PI3-kinase and mTOR inhibitors differently modulate the function of the ABCG2 multidrug transporter.
Biochem Bioph Res Co
420
, 869-74
9.
de Boussac H, Orbán TI, Várady G, Tihanyi B,
Bacquet C
, Brózik A,
Váradi A
,
Sarkadi B
and
Arányi T
(2012) [22922104]
Stimulus-induced expression of the ABCG2 multidrug transporter in HepG2 hepatocarcinoma model cells involves the ERK1/2 cascade and alternative promoters.
Biochem Bioph Res Co
426
, 172-6
10.
Le Saux O, Martin L, Aherrahrou Z, Leftheriotis G,
Váradi A
and Brampton CN (2012) [23248644]
The molecular and physiological roles of ABCC6: more than meets the eye.
Front Genet
3
, 289
11.
Váradi A
,
Szabó Z
,
Pomozi V
, de Boussac H,
Fülöp K
and
Arányi T
(2011) [21039331]
ABCC6 as a target in pseudoxanthoma elasticum.
Curr Drug Targets
12
, 671-82
12.
Szabó Z,
Váradi A
, Li Q and Uitto J (2011) [21813308]
ABCC6 does not transport adenosine - relevance to pathomechanism of pseudoxanthoma elasticum.
Mol Genet Metab
104
, 421; author reply 42
13.
Fülöp K
, Jiang Q, Wetering KV,
Pomozi V
, Szabó PT,
Arányi T
, Sarkadi B, Borst P, Uitto J and
Váradi A
(2011) [22056557]
ABCC6 does not transport vitamin K3-glutathione conjugate from the liver: relevance to pathomechanisms of pseudoxanthoma elasticum.
Biochem Bioph Res Co
415
, 468-71
14.
Le Saux O,
Fülöp K
, Yamaguchi Y,
Iliás A
,
Szabó Z
, Brampton CN,
Pomozi V
,
Huszár K
,
Arányi T
and
Váradi A
(2011) [21935449]
Expression and In Vivo Rescue of Human ABCC6 Disease-Causing Mutants in Mouse Liver.
PLoS ONE
6
, e24738
15.
Arányi T
,
Fülöp K
,
Symmons O
,
Pomozi V
and
Váradi A
(2011) [21082744]
Predictable difficulty or difficulty to predict.
Protein Sci
20
, 1-3; author reply 4-
16.
Brampton C, Yamaguchi Y, Vanakker O, Van Laer L, Chen LH, Thakore M, De Paepe A,
Pomozi V
, Szabó PT, Martin L,
Váradi A
and Le Saux O (2011) [21597330]
Vitamin K does not prevent soft tissue mineralization in a mouse model of pseudoxanthoma elasticum.
Cell Cycle
10
,
17.
Li Q, Sadowski S, Frank M, Chai C,
Váradi A
, Ho SY, Lou H, Dean M, Thisse C, Thisse B and Uitto J (2010) [20596085]
The abcc6a gene expression is required for normal zebrafish development.
J Invest Dermatol
130
, 2561-8
18.
de Boussac H
, Ratajewski M, Sachrajda I,
Köblös G
, Tordai A, Pulaski L,
Buday L
,
Váradi A
and
Arányi T
(2010) [20463007]
The ERK1/2-hepatocyte nuclear factor 4alpha axis regulates human ABCC6 gene expression in hepatocytes.
J Biol Chem
285
, 22800-8
19.
Köblös G
, Andrikovics H, Prohászka Z, Tordai A,
Váradi A
and
Arányi T
(2010) [19929409]
The R1141X loss-of-function mutation of the ABCC6 gene is a strong genetic risk factor for coronary artery disease.
Genet Test Mol Biomarkers
14
, 75-8
20.
Fülöp K
,
Barna L
,
Symmons O
,
Závodszky P
and
Váradi A
(2009) [19133228]
Clustering of disease-causing mutations on the domain-domain interfaces of ABCC6.
Biochem Bioph Res Co
379
, 706-9
21.
Hegedűs C, Ozvegy-Laczka C, Apáti A, Magócsi M, Német K, Orfi L, Kéri G, Katona M, Takáts Z,
Váradi A
,
Szakács G
and Sarkadi B (2009) [19785662]
Interaction of nilotinib, dasatinib and bosutinib with ABCB1 and ABCG2: implications for altered anti-cancer effects and pharmacological properties.
Brit J Pharmacol
158
, 1153-64
22.
Kasza I, Hegyi Z,
Szabo K
, Andrikovics H, Nemet K,
Varadi A
, Sarkadi B and Homolya L (2009) [20025763]
Model system for the analysis of cell surface expression of human ABCA1.
BMC Cell Biol
10
, 93
23.
Li Q, Jiang Q, Pfendner E,
Váradi A
and Uitto J (2009) [19054062]
Pseudoxanthoma elasticum: clinical phenotypes, molecular genetics and putative pathomechanisms.
Exp Dermatol
18
, 1-11
24.
Szeri F
,
Iliás A
,
Pomozi V
, Robinow S,
Bakos E
and
Váradi A
(2009) [19059376]
The high turnover Drosophila multidrug resistance-associated protein shares the biochemical features of its human orthologues.
Bba-biomembranes
1788
, 402-9
25.
Bors A, Ribiczey P,
Köblös G
, Brózik A, Ujfaludi Z, Magócsi M,
Váradi A
, Tordai A, Kovács T and
Arányi T
(2008) [17945177]
External cell control polymerase chain reaction: replacing internal standards with an unbiased strategy for quantitative polymerase chain reaction normalization.
Anal Biochem
372
, 261-3
26.
Symmons O
,
Váradi A
and
Arányi T
(2008) [18791038]
How segmental duplications shape our genome: recent evolution of ABCC6 and PKD1 Mendelian disease genes.
Mol Biol Evol
25
, 2601-13
27.
Özvegy-Laczka C, Laczkó R, Hegedűs C, Litman T, Várady G, Goda K, Hegedűs T, Dokholyan NV, Sorrentino BP,
Váradi A
and Sarkadi B (2008) [18644784]
Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter.
J Biol Chem
283
, 26059-70
28.
Szakács G
,
Váradi A
, Ozvegy-Laczka C and Sarkadi B (2008) [18468555]
The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox).
Drug Discov Today
13
, 379-393
29.
Telbisz A, Müller M, Ozvegy-Laczka C, Homolya L, Szente L,
Váradi A
and Sarkadi B (2007) [17662239]
Membrane cholesterol selectively modulates the activity of the human ABCG2 multidrug transporter.
Bba-biomembranes
1768
, 2698-713
30.
Müller M,
Klein I
, Kopácsi S, Remaley AT, Rajnavölgyi E, Sarkadi B and
Váradi A
(2006) [17055487]
Co-expression of human ABCG5 and ABCG8 in insect cells generates an androstan stimulated membrane ATPase activity.
FEBS Lett
580
, 6139-44
31.
Patocs A,
Klein I
, Szilvasi A, Gergics P, Toth M, Valkusz Z, Forizs E, Igaz P, Al-Farhat Y, Tordai A,
Varadi A
, Racz K and Esik O (2006) [16865647]
Genotype-phenotype correlations in Hungarian patients with hereditary medullary thyroid cancer.
Wien Klin Wochenschr
118
, 417-21
32.
Sarkadi B, Homolya L,
Szakács G
and
Váradi A
(2006) [17015488]
Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system.
Physiol Rev
86
, 1179-236
33.
Tusnády GE
, Sarkadi B,
Simon I
and
Váradi A
(2006) [16337630]
Membrane topology of human ABC proteins.
FEBS Lett
580
, 1017-22
34.
Arányi T
,
Váradi A
,
Simon I
and
Tusnády GE
(2006) [17022803]
The BiSearch web server.
BMC Bioinformatics
7
, 431
35.
Cervenak J, Andrikovics H, Ozvegy-Laczka C, Tordai A, Német K,
Váradi A
and Sarkadi B (2006) [16337740]
The role of the human ABCG2 multidrug transporter and its variants in cancer therapy and toxicology.
Cancer Lett
234
, 62-72
36.
Tusnády GE
,
Simon I
,
Váradi A
and
Arányi T
(2005) [15653630]
BiSearch: primer-design and search tool for PCR on bisulfite-treated genomes.
Nucleic Acids Res
33
, e9
37.
Ozvegy-Laczka C, Várady G,
Köblös G
, Ujhelly O, Cervenak J, Schuetz JD, Sorrentino BP, Koomen GJ,
Váradi A
, Német K and Sarkadi B (2005) [15557326]
Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interaction with a monoclonal antibody on the cell surface.
J Biol Chem
280
, 4219-27
38.
Cortés-Selva F, Muñoz-Martínez F,
Iliás A
, Jiménez AI,
Váradi A
, Gamarro F and Castanys S (2005) [15737615]
Functional expression of a multidrug P-glycoprotein transporter of Leishmania.
Biochem Bioph Res Co
329
, 502-7
39.
Arányi T
, Ratajewski M, Bardóczy V, Pulaski L, Bors A, Tordai A and
Váradi A
(2005) [15760889]
Identification of a DNA methylation-dependent activator sequence in the pseudoxanthoma elasticum gene, ABCC6.
J Biol Chem
280
, 18643-50
40.
Elkind NB, Szentpétery Z, Apáti A, Ozvegy-Laczka C, Várady G, Ujhelly O,
Szabó K
, Homolya L,
Váradi A
,
Buday L
, Kéri G, Német K and Sarkadi B (2005) [15753373]
Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor Iressa (ZD1839, Gefitinib).
Cancer Res
65
, 1770-7
41.
Ozvegy-Laczka C,
Köblös G
, Sarkadi B and
Váradi A
(2005) [15670731]
Single amino acid (482) variants of the ABCG2 multidrug transporter: major differences in transport capacity and substrate recognition.
Bba-biomembranes
1668
, 53-63
42.
Sarkadi B, Ozvegy-Laczka C, Német K and
Váradi A
(2004) [15165903]
ABCG2 -- a transporter for all seasons.
FEBS Lett
567
, 116-20
43.
Cserepes J, Szentpétery Z, Seres L, Ozvegy-Laczka C, Langmann T, Schmitz G, Glavinas H,
Klein I
, Homolya L,
Váradi A
, Sarkadi B and Elkind NB (2004) [15240127]
Functional expression and characterization of the human ABCG1 and ABCG4 proteins: indications for heterodimerization.
Biochem Bioph Res Co
320
, 860-7
44.
Szentpétery Z, Sarkadi B,
Bakos E
and
Váradi A
(2004) [15152943]
Functional studies on the MRP1 multidrug transporter: characterization of ABC-signature mutant variants.
Anticancer Res
24
, 449-55
45.
Kern A, Szentpétery Z,
Liliom K
,
Bakos E
, Sarkadi B and
Váradi A
(2004) [14759224]
Nucleotides and transported substrates modulate different steps of the ATPase catalytic cycle of MRP1 multidrug transporter.
Biochem J
380
, 549-60
46.
Tarnay JN,
Szeri F
,
Iliás A
, Annilo T, Sung C, Le Saux O,
Váradi A
, Dean M, Boyd CD and Robinow S (2004) [15373810]
The dMRP/CG6214 gene of Drosophila is evolutionarily and functionally related to the human multidrug resistance-associated protein family.
Insect Mol Biol
13
, 539-48
47.
Szentpétery Z, Kern A,
Liliom K
, Sarkadi B,
Váradi A
and
Bakos E
(2004) [15252017]
The role of the conserved glycines of ATP-binding cassette signature motifs of MRP1 in the communication between the substrate-binding site and the catalytic centers.
J Biol Chem
279
, 41670-8
48.
Andrikovics H,
Klein I
, Bors A, Nemes L, Marosi A,
Váradi A
and Tordai A (2003) [12857556]
Analysis of large structural changes of the factor VIII gene, involving intron 1 and 22, in severe hemophilia A.
Haematol-hematol J
88
, 778-84
49.
Ujhelly O, Ozvegy C, Várady G, Cervenak J, Homolya L, Grez M, Scheffer G, Roos D, Bates SE,
Váradi A
, Sarkadi B and Német K (2003) [12659681]
Application of a human multidrug transporter (ABCG2) variant as selectable marker in gene transfer to progenitor cells.
Hum Gene Ther
14
, 403-12
50.
Hegedüs T, Sessler T, Scott R, Thelin W,
Bakos E
,
Váradi A
, Szabó K, Homolya L, Milgram SL and Sarkadi B (2003) [12615054]
C-terminal phosphorylation of MRP2 modulates its interaction with PDZ proteins.
Biochem Bioph Res Co
302
, 454-61
51.
Bodó A,
Bakos É
,
Szeri F
,
Váradi A
and Sarkadi B (2003) [12704183]
Differential modulation of the human liver conjugate transporters MRP2 and MRP3 by bile acids and organic anions.
J Biol Chem
278
, 23529-37
52.
Homolya L,
Váradi A
and Sarkadi B (2003) [12897433]
Multidrug resistance-associated proteins: Export pumps for conjugates with glutathione, glucuronate or sulfate.
Biofactors
17
, 103-14
53.
Sinkó E,
Iliás A
, Ujhelly O, Homolya L, Scheffer GL, Bergen AA, Sarkadi B and
Váradi A
(2003) [12901863]
Subcellular localization and N-glycosylation of human ABCC6, expressed in MDCKII cells.
Biochem Bioph Res Co
308
, 263-9
54.
Bodó A,
Bakos E
,
Szeri F
,
Váradi A
and Sarkadi B (2003) [12676459]
The role of multidrug transporters in drug availability, metabolism and toxicity.
Toxicol Lett
140-141
, 133-43
55.
Ozvegy C,
Váradi A
and Sarkadi B (2002) [12374800]
Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation.
J Biol Chem
277
, 47980-90
56.
Hegedus T, Orfi L, Seprodi A,
Váradi A
, Sarkadi B and Kéri G (2002) [12084474]
Interaction of tyrosine kinase inhibitors with the human multidrug transporter proteins, MDR1 and MRP1.
Bba-mol Basis Dis
1587
, 318-25
57.
Iliás A
, Urbán Z, Seidl TL, Le Saux O,
Sinkó E
, Boyd CD, Sarkadi B and
Váradi A
(2002) [11880368]
Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6).
J Biol Chem
277
, 16860-7
58.
Igaz P, Patócs A, Rácz K,
Klein I
,
Váradi A
and Esik O (2002) [12050290]
Occurrence of pheochromocytoma in a MEN2A family with codon 609 mutation of the RET proto-oncogene.
J Clin Endocr Metab
87
, 2994
59.
Váradi A
,
Szakács G
,
Bakos E
and Sarkadi B (2002) [11990782]
P glycoprotein and the mechanism of multidrug resistance.
Novartis Found Symp
243
, 54-65; discussion 65
60.
Klein I
, Andrikovics H, Bors A, Nemes L, Tordai A and
Váradi A
(2001) [11380636]
A haemophilia A and B molecular genetic diagnostic programme in Hungary: a highly informative and cost-effective strategy.
Haemophilia
7
, 306-12
61.
Szakács G
, Langmann T, Ozvegy C, Orsó E, Schmitz G,
Váradi A
and Sarkadi B (2001) [11700048]
Characterization of the ATPase cycle of human ABCA1: implications for its function as a regulator rather than an active transporter.
Biochem Bioph Res Co
288
, 1258-64
62.
Ozvegy C, Litman T,
Szakács G
, Nagy Z, Bates S,
Váradi A
and Sarkadi B (2001) [11437380]
Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells.
Biochem Bioph Res Co
285
, 111-7
63.
Klein I
, Esik O, Homolya V,
Szeri F
and
Váradi A
(2001) [11524247]
Molecular genetic diagnostic program of multiple endocrine neoplasia type 2A and familial medullary thyroid carcinoma syndromes in Hungary.
J Endocrinol
170
, 661-6
64.
Szakács G
, Özvegy C,
Bakos É
, Sarkadi B and
Váradi A
(2001) [11336637]
Role of glycine-534 and glycine-1179 of human multidrug resistance protein (MDR1) in drug-mediated control of ATP hydrolysis.
Biochem J
356
, 71-5
65.
Bakos É
, Evers R, Calenda G,
Tusnády GE
,
Szakács G
,
Váradi A
and Sarkadi B (2000) [11082039]
Characterization of the amino-terminal regions in the human multidrug resistance protein (MRP1).
J Cell Sci
113 (Pt 2)
, 4451-61
66.
Kern A, Felföldi F, Sarkadi B and
Váradi A
(2000) [10891347]
Expression and characterization of the N- and C-terminal ATP-binding domains of MRP1.
Biochem Bioph Res Co
273
, 913-9
67.
Bakos É
, Evers R, Sinkó E,
Váradi A
, Borst P and Sarkadi B (2000) [10727523]
Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions.
Mol Pharmacol
57
, 760-8
68.
Smith AJ, van Helvoort A, van Meer G, Szabó K,
Welker E
,
Szakács G
,
Varadi A
, Sarkadi B and Borst P (2000) [10918072]
MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping.
J Biol Chem
275
, 23530-9
69.
Szakács G
, Özvegy C,
Bakos É
, Sarkadi B and
Váradi A
(2000) [11027628]
Transition-state formation in ATPase-negative mutants of human MDR1 protein.
Biochem Bioph Res Co
276
, 1314-9
70.
Welker E
and
Váradi A
(2000) [10799330]
Vectors with hidden cloning sites.
Biochem Bioph Res Co
271
, 534-6
71.
Klein I
, Sarkadi B and
Váradi A
(1999) [10581359]
An inventory of the human ABC proteins.
Bba-biomembranes
1461
, 237-62
72.
Sharom FJ, Yu X, Lu P, Liu R, Chu JW, Szabó K, Müller M, Hose CD, Monks A,
Váradi A
, Seprôdi J and Sarkadi B (1999) [10413294]
Interaction of the P-glycoprotein multidrug transporter (MDR1) with high affinity peptide chemosensitizers in isolated membranes, reconstituted systems, and intact cells.
Biochem Pharmacol
58
, 571-86
73.
Andrikovics H,
Klein I
,
Kalmár L
, Bors A, Jermendy G, Petri I, Kalász L,
Váradi A
and Tordai A (1999) [10586619]
[A new method of molecular testing in the differential diagnosis of hereditary hemochromatosis]
Orv Hetil
140
, 2517-22
74.
Klein I
, Homolya V,
Váradi A
and Esik O (1999) [10628190]
[Molecular genetic study of medullary thyroid cancer]
Orv Hetil
140
, 2739-46
75.
Szabó K,
Welker E
,
Bakos É
, Müller M, Roninson I,
Váradi A
and Sarkadi B (1998) [9553060]
Drug-stimulated nucleotide trapping in the human multidrug transporter MDR1. Cooperation of the nucleotide binding domains.
J Biol Chem
273
, 10132-8
76.
Bakos É
, Evers R,
Szakács G
,
Tusnády GE
,
Welker E
,
Szabó K
, de Haas M, van Deemter L, Borst P,
Váradi A
and Sarkadi B (1998) [9822694]
Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain.
J Biol Chem
273
, 32167-75
77.
Klein I
and
Varadi A
(1998) [-100002664]
Géntudósok.
Természet Világa
129
, 230-231
78.
Tordai A, Andrikovics H,
Kalmár L
, Rajczy K, Pénzes M, Sarkadi B,
Klein I
and
Váradi A
(1998) [9783719]
High frequency of the haemochromatosis C282Y mutation in Hungary could argue against a Celtic origin of the mutation.
J Med Genet
35
, 878-9
79.
Váradi A
,
Tusnády GE
,
Bakos É
and Sarkadi B (1998) [19002784]
Membrane topology of human MRP homologs
Cytotechnology
27
, 71-79
80.
Tusnády GE
and
Váradi A
(1998) [9464238]
Short MRP may not be short.
Biochem Bioph Res Co
242
, 465-6
81.
Klein I
, Tordai A, Nemes L, Sas G and
Váradi A
(1998) [9528291]
[Indirect methods in the genetic diagnosis of hemophilia A]
Orv Hetil
139
, 487-91
82.
Falus A,
Váradi A
and Raskó I (1998) [9595930]
[The DNA-chip, a new tool for medical genetics]
Orv Hetil
139
, 957-60
83.
Bakos É
,
Klein I
,
Welker E
, Szabó K, Müller M, Sarkadi B and
Váradi A
(1997) [9169612]
Characterization of the human multidrug resistance protein containing mutations in the ATP-binding cassette signature region.
Biochem J
323 (Pt 3)
, 777-83
84.
Falus A,
Varadi A
and Rasko I (1997) [-100002660]
DNS chipek: a molekuláris genetika új korszaka.
Természet Világa
11
, 491
85.
Tusnády GE
,
Bakos É
,
Váradi A
and Sarkadi B (1997) [9013845]
Membrane topology distinguishes a subfamily of the ATP-binding cassette (ABC) transporters.
FEBS Lett
402
, 1-3
86.
Szabó K,
Bakos É
,
Welker E
, Müller M, Goodfellow HR, Higgins CF,
Váradi A
and Sarkadi B (1997) [9287320]
Phosphorylation site mutations in the human multidrug transporter modulate its drug-stimulated ATPase activity.
J Biol Chem
272
, 23165-71
87.
Tordai A,
Klein I
, Rajczy K, Pénzes M, Sarkadi B and
Váradi A
(1997) [9375776]
Prevalence of factor V Leiden (Arg506Gln) in Hungary.
Brit J Haematol
99
, 466-7
88.
Ferenczi A, Homolya V,
Szakács G
, Németh K, Kiss E,
Váradi A
and Fekete G (1997) [9072754]
[Clinical application of analysis of microsatellite markers in the prenatal diagnosis of cystic fibrosis]
Orv Hetil
138
, 209-13
89.
Müller M,
Bakos É
,
Welker E
,
Váradi A
, Germann UA, Gottesman MM, Morse BS, Roninson IB and Sarkadi B (1996) [8567633]
Altered drug-stimulated ATPase activity in mutants of the human multidrug resistance protein.
J Biol Chem
271
, 1877-83
90.
Németh K, Fekete G, Kiss E,
Váradi A
, Holics K and Ujhelyi R (1996) [8803789]
Analysis of five CFTR mutations in Hungarian cystic fibrosis patients.
J Inherit Metab Dis
19
, 378
91.
Bakos É
, Hegedűs T, Holló Z,
Welker E
,
Tusnády GE
, Zaman GJ, Flens MJ,
Váradi A
and Sarkadi B (1996) [8647833]
Membrane topology and glycosylation of the human multidrug resistance-associated protein.
J Biol Chem
271
, 12322-6
92.
Németh K, Holics K, Ujhelyi R,
Váradi A
and Fekete G (1996) [8649752]
[Analysis of five mutations of cystic fibrosis occurring in the Hungarian population]
Orv Hetil
137
, 899-903
93.
Welker E
, Szabó K, Holló Z, Müller M, Sarkadi B and
Váradi A
(1995) [7488154]
Drug-stimulated ATPase activity of a deletion mutant of the human multidrug-resistance protein (MDR1).
Biochem Bioph Res Co
216
, 602-9
94.
Magyar A,
Bakos É
and
Váradi A
(1995) [7575407]
Structure and tissue-specific expression of the Drosophila melanogaster organellar-type Ca(2+)-ATPase gene.
Biochem J
310 (Pt 3)
, 757-63
95.
Fekete G,
Váradi A
, Pipiras E, Németh K, Réthy LA, Holics K and Ujhelyi R (1992) [1408077]
[Detection of delta F508 mutation in cystic fibrosis]
Orv Hetil
133
, 2423-4, 2427-30
96.
Magyar A and
Váradi A
(1990) [2148477]
Molecular cloning and chromosomal localization of a sarco/endoplasmic reticulum-type Ca2(+)-ATPase of Drosophila melanogaster.
Biochem Bioph Res Co
173
, 872-7
97.
Váradi A
, Gilmore-Heber M and Benz EJ (1989) [2557235]
Amplification of the phosphorylation site-ATP-binding site cDNA fragment of the Na+,K(+)-ATPase and the Ca2(+)-ATPase of Drosophila melanogaster by polymerase chain reaction.
FEBS Lett
258
, 203-7
98.
Váradi A
and Scheraga HA (1986) [2937452]
Localization of segments essential for polymerization and for calcium binding in the gamma-chain of human fibrinogen.
Biochemistry-us
25
, 519-28
99.
Váradi A
and
Patthy L
(1984) [6722138]
Beta(Leu121-Lys122) segment of fibrinogen is in a region essential for plasminogen binding by fibrin fragment E.
Biochemistry-us
23
, 2108-12
100.
Patthy L
,
Trexler M
, Váli Z,
Bányai L
and
Váradi A
(1984) [6373375]
Kringles: modules specialized for protein binding. Homology of the gelatin-binding region of fibronectin with the kringle structures of proteases.
FEBS Lett
171
, 131-6
101.
Horwitz BH,
Váradi A
and Scheraga HA (1984) [6592597]
Localization of a fibrin gamma-chain polymerization site within segment Thr-374 to Glu-396 of human fibrinogen.
P Natl Acad Sci Usa
81
, 5980-4
102.
Bányai L
,
Váradi A
and
Patthy L
(1983) [6685059]
Common evolutionary origin of the fibrin-binding structures of fibronectin and tissue-type plasminogen activator.
FEBS Lett
163
, 37-41
103.
Váradi A
and
Patthy L
(1983) [6222763]
Location of plasminogen-binding sites in human fibrin(ogen).
Biochemistry-us
22
, 2440-6
104.
Váradi A
and
Patthy L
(1981) [6797430]
Kringle 5 of human plasminogen carries a benzamidine-binding site.
Biochem Bioph Res Co
103
, 97-102
105.
Varadi A
and Pongor S (1979) [-100002732]
Determination of sulfur-containing amino-acids by quantitative\n ion-exchange thin-layer chromatography
J Chromatogr A
173
, 419-424
106.
Patthy L
,
Varadi A
, Thesz J and Kovacs K (1979) [499203]
Identification of the C-1-phosphate-binding Arginine Residue of Rabbit-muscle Aldolase - Isolation of 1,2-cyclohexanedione-labeled Peptide by Chemisorption Chromatography
Eur J Biochem
99
, 309-13
107.
Cseke E,
Váradi A
, Szabolcsi G and Biszku E (1978) [729779]
On the molecular sieving property of the human erythrocyte membrane and the localization of some glycolytic enzymes in the cell.
FEBS Lett
96
, 15-8
108.
Váradi A
, Pongor S and Kaul AK (1976) [1007888]
Quantitative determination of methionine in proteins: gas chromatography of methylthiocyanate liberated by cleavage with cyanogen bromide.
Acta Biochim Biophys Acad Sci Hung
11
, 87-93
109.
Holderith J, Toth T and
Varadi A
(1975) [-100002733]
Minimizing time for gas-chromatographic analysis - finding optimum\n measuring parameters by means of a simplex method
Magyar Kémiai folyóirat
81
, 162-164
110.
Váradi A
(1975) [1133142]
Thin-layer chromatography on a chromatosheet coated with resin in different ionic forms for the separation of amino acid mixtures containing asparagine and glutamine.
J Chromatogr A
110
, 166-70
Books or book chapters
1.
Homolya L,
Varadi A
and Sarkadi B (2002)
Multidrug Resistance-Associated Proteins: Export Pumps for Conjugates with Glutathione,Glucuronate or Sulfate.
Thiol Metabolism and Redox Regulation of Cellular Functions
, 107
2.
Váradi A
,
Tusnády GE
and Sarkadi B (2002)
Membrane topology of human ABC proteins.
The book of ABC proteins
, 37-47
3.
Varadi A
,
Szakács G
,
Bakos E
and Sarkadi B (2002)
P glycoprotein and the Mechanism of Multidrug Resistance
Mechanisms of Drug Resistance in Epilepsy
ISBN: 047084146X
,
4.
Váradi A
,
Tusnády GE
,
Bakos É
and Sarkadi B (1998)
Membrane topology of the human multidrug resistance-associated protein (MRP) and its homologs.
Multiple drug resistance in cancer: molecular, cellular and clinical aspects.
, 71-80
5.
Varadi A
(1997)
Színlátás.
Molekuláris medicina
, 244-247
6.
Varadi A
(1997)
Hemofilia A és B.
Molekuláris medicina
, 221-227
7.
Varadi A
(1997)
A génhibák felderitésének módszerei.
Molekuláris medicina
, 86-89
8.
Varadi A
and Papp Z (1995)
Klinikai molekularis genetika.
, 103-121
9.
Patthy L
,
Trexler M
,
Váli Z
,
Bányai L
and
Váradi A
(1984)
Kringle structures of human plasminogen: their role in the regulation of fibrinolysis.
Symp.Biol.Hung.
25
, 73-79